And this happens normally during development, for instance, in the development of the hand, that normally to begin with, the hand looks very much like a duck paddle foot and the webs between the fingers. Those cells apoptose, giving you the fingers.
There are human conditions where that ceases to where apoptosis just does not happen and people are born with web feet. Apoptosis normally happens in cells that have been around in the body long enough that they're kind of worn out, and so they need to make way for nice, new young cells.
When that doesn't happen, that's cancer. And so apoptosis can be normal, and in the absence of apoptosis, that can lead to cancer.
Too much apoptosis in an otherwise normal human being will result in a number of so-called neurodegenerative diseases where cells die when they're not supposed to die. And they get messages from some place, most of which we don't understand, to tell them to die, so in a certain part of the lower part of the brain, that's what causes Parkinson's disease.
This also characterizes Huntington's disease, and Alzheimer's disease, and Lou Gehrig's disease, and a number of other neurodegenerative diseases. View all volumes in this series: Current Topics in Developmental Biology.
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Apoptosis involves the death of a cell, but it benefits the organism as a whole (for instance, by letting fingers develop or eliminating potential cancer cells). In this. Jun 8, Apoptosis, or programmed cell death, is a mechanism in embryonic development that occurs naturally in organisms. Apoptosis is a different process from cell necrosis, which is uncontrolled cell death usually after infection or specific trauma. Sydney Brenner, H. Robert Horvitz, and.
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Continues the legacy of this premier serial with quality chapters authored by leaders in the field Includes descriptions of the most recent advances in the field Covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila. Powered by. You are connected as.
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